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Histochemical Survey of Brain Tumor Enzymes
J. S. O'CONNOR, MD;
E. R. LAWS, JR., MD
Arch Neurol. 1963;9(6):641-651.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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A previous report from this laboratory described the results of a histochemical study of five enzyme systems in 30 brain tumors.1 An additional 30 tumors have been studied in greater detail, so that this report concerns the histochemical observations on ten enzyme systems of neoplasms of the central nervous system.
Materials and Methods
The material consisted of 30 surgical specimens including 9 meningiomas, 13 gliomas, and 8 miscellaneous intracranial tumors. Specimens were obtained at operation and immediately immersed in an isopentane solid carbon dioxide (Dry Ice) bath and then stored for short periods at —20 C. Sections, cut on a cryostat at a thickness of 6µ and mounted on glass slides, were placed in the appropriate incubation media. In every case additional tumor specimens were processed for routine histological study, and cytological diagnosis was established after review by the staff and neuropathologist.
Established histochemical methods were employed in the
. . . [Full Text PDF of this Article]
Author Affiliations
BALTIMORE
Footnotes
Submitted for publication May 8, 1963; accepted Sept 3.
This work was done in the Division of Neurological Surgery, Johns Hopkins Hospital.
This work was supported by a US Public Health Service research grant.
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