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GEORGE A. JERVIS, MD

Arch Neurol. 1963;9(3):244-257.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Huntington's chorea is generally considered to be a disease of the adult. In a recent analysis of 762 patients, Wendt¹ calculated the mean age of onset of clinical manifestations at 44 years of age and reported that in 64% of the patients the onset was between 35 and 55 years. However, cases with onset before the age of ten years have been mentioned repeatedly in the extensive medical literature on Huntington's chorea. The description of these patients is usually brief and often incomplete with little or no follow-up. In only a few reports was the clinical diagnosis confirmed by pathological examination. Clinical recognition of the disease in children may offer considerable difficulty because typical choreatic movements are often absent, the presenting symptomatology being one of hypokinesia, muscular rigidity, epilepsy, and mental retardation.

The purpose of this report is to describe the clinical, pathological, and genetical data of four children . . . [Full Text PDF of this Article]

Author Affiliations
THIELLS, NY

From the Research Department, Letchworth Village, New York State Department of Mental Hygiene.

Footnotes
Submitted for publication May 21, 1963; accepted May 27, 1963.

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