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Response Characteristic for Normal Aging Subjects

RALPH ROSSEN, M.D.; ERNST SIMONSON, M.D.; JOHN BAKER, M.D.

Arch Neurol. 1963;8(4):373-381.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

As a sequence to the evaluation of the electroencephalogram (EEG) in normal aging men exposed to mild hypoxia,¹⁷ a similar study was instituted using carbon dioxide in low concentration as a stress agent toward a better understanding of the normal aging process,^16,21 and early cerebrovascular disease.^2,3,13

We have reviewed the electroencephalographic (EEG) pattern and the relationship of alveolar CO₂ and pulmonary ventilation to the EEG in normal young and older subjects, whose mean ages were 24.4 years and 60.7 years respectively, during breathing a CO₂ gas mixture.

Particular attention was given to the older subjects whose aging process had been uncomplicated by detectable disease. Analysis of the EEG pattern was made within and just without the normal range, since it became apparent early in the study that 6% CO₂ inhalation for 10 minutes produced only slight transitory changes and no apparent clinical symptoms.

Certain . . . [Full Text PDF of this Article]

Author Affiliations
MINNEAPOLIS

From the Laboratory of Physiological Hygiene, University of Minnesota, and L. E. Phillips Psychobiological Laboratory, Mount Sinai Hospital, Minneapolis.

Footnotes
Received for publication Nov. 21, 1962.

This study was supported in part by Grant B-1859 C3, National Institutes of Health, U.S. Public Health Service.

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