This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Changes in Brain Stem Conduction, Excitability, and Sensitivity to Anesthesia in Adrenalectomized Cats

SHAUL FELDMAN, M.D.

Arch Neurol. 1962;7(5):460-470.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Since the classical observations made by Addison on disturbances occurring in patients suffering from adrenocortical insufficiency, various neurological and mental alterations have suggested that the vital hormones are essential for normal function of the central nervous system. The mental changes in these patients consist among others of irritability, unexplained bursts of anger, disturbed sleep with nightmares, depression, periods of amnesia and unreality, and occasionally hallucinations and paranoid psychosis.^1-4 Some of the patients exhibit motor and sensory disturbances, changes in reflexes, pupillary and visual abnormalities, drowsiness, and confusion, which is occasionally accompanied by convulsions.^1-3 Among other abnormalities described in hypoadrenalism are slowing of the EEG in patients^1,2,5,6 and experimental animals⁷ and an increase in brain excitability of the latter,^8,9 as determined by the threshold for electrically induced seizures.

Various metabolic derangements in the central nervous system have been described in hypoadrenalism,⁹ but there is very . . . [Full Text PDF of this Article]

Author Affiliations
JERUSALEM, ISRAEL

Department of Nervous Diseases (Laboratory of Experimental Neurology), Hadassah University Hospital and the Hebrew University-Hadassah Medical School.

Footnotes
Submitted for publication April 17, 1962.

This investigation was supported wholly by Grant No. 244 from the National Multiple Sclerosis Society.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati     What's this?