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Studies During the Acute and Recovery Phase

AUGUSTA McCORD, Ph.D.; R. D. BROOKE WILLIAMS, M.D.

Arch Neurol. 1962;7(5):427-431.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Introduction

An intravenous injection of glucose normally causes the glucose content of the cerebrospinal fluid to rise, and there is a consistent pattern of change of concentration in the cisternal and lumbar spinal fluid. We have previously reported studies describing the normal pattern for glucose diffusion in patients^1,2 and have obtained comparable findings on dogs.³ Similar diffusion patterns have been observed using a variety of different diffusible substances.^4,5,6 Glucose diffusion in patients results in a normal maximum rise of both lumbar and cisternal curves greater than 30 mg/100 ml. above the initial values.^1,2,7 Figure 1 shows a typical set of such normal curves which were obtained in a small infant with cerebral palsy, the cisternal curve showing higher values than the lumbar curve.

Studies on glucose diffusion in acute tuberculous meningitis have sometimes previously shown a reversal of the normal pattern for the lumbar and cisternal . . . [Full Text PDF of this Article]

Author Affiliations
LOUISVILLE

Department of Pediatrics, School of Medicine and Dentistry, University of Rochester, Rochester, N.Y.

Footnotes
Submitted for publication March 22, 1962.

Supported in part by the American Medical Association Grant No. 299, National Institutes of Health Grant No. B1599.

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