This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (16)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Report of a Case, Including Response to Curare Therapy

RICHARD M. STEIDL; ARTHUR J. OSWALD; FREDERIC J. KOTTKE

Arch Neurol. 1962;6(6):451-461.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Defects in neuromuscular transmission suggestive of myasthenia gravis have been found in association with a wide variety of disorders, including hyperthyroidism,^1-8 myopathies,^9-10 lupus erythematosis,^11-12 malignancy,^13-15 and polymyositis.¹⁶ A similar relationship has been reported in various neuropathies, viz., poliomyelitis,^17-19 syringomyelia,^1,20 amyotrophic lateral sclerosis,^2,16,18,21 and a variety of other conditions affecting the anterior horn cells²²; however, in none of these cases did myasthenia gravis appear as the primary disease.

This report is a study of a patient with apparent myasthenia gravis who developed striking resistance to conventional therapy, who ultimately proved to respond in part to repeated courses of "rest" therapy with curare, and who late in her illness showed unexpected evidence of motor neuron disease.

Report of Case

During November, 1955, it was noted that the patient, a previously healthy 12-year-old girl, was unable to smile, and that the corners of . . . [Full Text PDF of this Article]

Author Affiliations
MINNEAPOLIS

From the Departments of Laboratory Medicine, Physical Medicine and Rehabilitation, and Anesthesiology, University of Minnesota Medical School.

Instructor in Laboratory Medicine and in Physical Medicine and Rehabilitation (Dr. Steidl); Instructor in Anesthesiology (Dr. Oswald), and Professor and Head, Department of Physical Medicine and Rehabilitation (Dr. Kottke), University of Minnesota Medical School.

Footnotes
Received for publication Dec. 21, 1961.

Supported by a grant from the Elizabeth Kenny Foundation, and Research Grants 1893 (C5) and B2900 from the U.S. Public Health Service.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?