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MARIA WOLLEMANN; LASZLO ZOLTAN

Arch Neurol. 1962;6(2):161-167.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Since the 1930's, the metabolism of acetylcholine has stood in the foreground of researches into the chemistry of the nervous system.¹ It has been demonstrated by several authors^2-4 that the metabolism of acetylcholine has a different rate in different parts of the central system. The cortex, the ganglia of the brain stem, and the gray matter of the cerebellum hydrolyze acetylcholine and acetylbetamethylcholine at a rapid rate and do not, or hardly, affect butyrylcholine, so that, in this respect, they behave like cholinesterase, contained in the erythrocytes and the muscles. White matter, on the other hand, splits butyrylcholine at a rapid and acetylcholine at a slower rate, while it produces no, or hardly any, effect on actylbetamethylcholine, being in this respect similar to blood serum. The function of butyrylcholinesterase (BuChE) in the white matter until now is not known. Our opinion is that the physiological role of BuChE . . . [Full Text PDF of this Article]

Author Affiliations
BUDAPEST, HUNGARY

Footnotes
Received for publication June 19, 1961.

National Institute of Neurosurgery, Budapest.

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