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Alzheimer Disease and Frontotemporal Dementia
Luca Rozzini, MD;
Giulia Lussignoli, MD;
Alessandro Padovani, PhD;
Angelo Bianchetti, MD;
Marco Trabucchi, MD
Alzheimer's Disease Unit S. Cuore Fatebenefratelli Hospital Via Pilastroni 4 25123 Brescia, Italy
Arch Neurol. 1997;54(4):350.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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In a recent article Levy and colleagues1 reported the preliminary results of a study aimed to investigate behavioral difference between Alzheimer disease (AD) and frontotemporal dementia (FTD) by using the Neuropsychiatric Inventory (NPI) scale, a standardized instrument that allows the assessment of several behavioral disturbances occurring in dementing illnesses. They found that disinhibition, apathy, aberrant motor behavior, and euphoria were significantly more elevated in patients with FTD, and conclude that the NPI reliably differentiates degenerative syndromes with anterior or posterior cerebral involvement and helps to characterize the behavioral syndromes of FTD and AD.1
In this investigation we used the Italian version of the NPI2 to assess behavioral disturbances in 100 patients with probable AD and 21 with FTD. Patients with FTD underwent technetium Tc 99m single photon emission computed tomography as a part of their diagnostic assessment.
The mean (±SD) composite subscale scores (frequency x severity) in
. . . [Full Text PDF of this Article]
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