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P. N. Cooper, MA, BM; M. Jackson, MBBS; G. Lennox, MABM; J. Lowe, DM; D. M. A. Mann, PhD
Department of Neurology Royal Salford Hospitals Hope Hospital Stott Lane Ave Salford, Manchester M6 8HD, England

Arch Neurol. 1996;53(9):836.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

We would like to clarify details of patients whom we have previously described,¹ with inclusions characteristic of extramotor involvement in motor neuron disease (MND)—type dementia. Of 11 cases reported, 7 had no evidence of motor weakness while alive. We can now report that of these 7, only 3 showed ubiquitinated inclusions in brain-stem nuclei; because of limited autopsy consent, the spinal cord was not available in these cases.

We would therefore like to clarify our discussion: paragraph 2 on page 1014 concerns the "extramotor cortical pathologic features of MND," but the third sentence should have made it clear that these patients have pathologic changes of MND, not of amyotrophic lateral sclerosis. As spinal cord tissue was not available, we cannot comment on the presence or absence of anterior horn cell inclusions in these cases. . . . [Full Text PDF of this Article]

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