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  Vol. 52 No. 8, August 1995 TABLE OF CONTENTS
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Anterograde Memory Impairment in Pick's Disease-Reply

John R. Hodges, MD
University of Cambridge Neurology Unit Addenbrooke's Hospital Hills Road Cambridge, England CB2 2QQ

Jennifer Gurd, PhD
Oxford, England

Arch Neurol. 1995;52(8):742-743.

Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

In reply

Beeson and colleagues raised the very interesting possibility that pathologic damage to the frontal lobe alone may be adequate to explain our patient's poor anterograde memory performance. As they point out, there is growing evidence to support the role of frontal lobes in memory processing, although I think they would agree that the role of the medial temporal lobes is much more secure in this context. In support of their argument, Beeson et al point out that our patient did not exhibit semantic memory loss or a pattern of remote memory loss consistent with temporal lobe pathologic findings at the time of testing. This is, however, not a strong argument, since patients with severe pathologic findings in the hippocampus may exhibit marked anterograde amnesia, without either retrograde memory impairment or deficits in semantic memory, as demonstrated by studies such as those performed on patient RB.1 Also, we . . . [Full Text PDF of this Article]



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