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ALBERT HEYMAN, M.D.; M. DEAN NEFZGER, Ph.D.; E. HARVEY ESTES, JR., M.D.

Arch Neurol. 1961;5(3):264-268.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

For many years hypercholesterolemia has been associated with the development of atherosclerosis in experimental animals and with an increased incidence of coronary thrombosis in man. The correlation between elevated serum cholesterol and atherosclerotic heart disease has led to the therapeutic use of cholesterol-reducing diets and medications in patients with this disorder. On the other hand, the correlation between cerebral thrombosis and hypercholesterolemia has been less well studied, and efforts to reduce serum cholesterol in this form of atherosclerosis have not been widely recommended. Patients with cerebral atherosclerosis might be expected to have an elevation of serum cholesterol comparable to that found in coronary vascular disease; however, differences in age, sex, and racial incidence of the 2 diseases could possibly produce differences in the level of this serum lipid. Coronary thrombosis, for example, occurs much more frequently in males,¹ appears in lower age groups,² and has a lower incidence . . . [Full Text PDF of this Article]

Author Affiliations
DURHAM, N.C.; WASHINGTON, D.C.; DURHAM, N.C.

From the Department of Medicine, (Neurology and Cardiology Divisions), Veterans Administration Hospital, and Duke University Medical Center, and from the National Academy of Sciences, National Research Council, Division of Medical Research.

Footnotes
Received for publication April 22, 1961.

Supported in part by research grants HTS-5369 and H-1217 from the National Heart Institute, National Institutes of Health, U.S. Public Health Service, and from the Committee on Aging, Neurology Section, Veterans Administration.

Associate Professor of Medicine, Duke University Medical Center, and Chief, Neurology Section, Veterans Administration Hospital, Durham (Dr. Heyman); Division of Medical Research, National Academy of Sciences, National Research Council, (Dr. Nefzger), and Associate Professor of Medicine, Duke University Medical Center, and Chief, Medical Service, Veterans Administration Hospital, Durham (Dr. Estes).

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