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Richard A. Rudick, MD

Arch Neurol. 1992;49(7):685-686.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

In this issue of the ARCHIVES, Capra et al¹ report the results of biweekly magnetic resonance imaging (MRI) in 10 patients with relapsing-remitting multiple sclerosis (MS). A total of 93 gadolinium-pentetic acid (GdDTPA)-enhancing lesions were observed in eight patients studied during a 3-month period. Of the enhancing lesions, 88% were in the supratentorial white matter, 9% were in the brain stem or cerebellum, and 3% were in the cervical spinal cord. Seventy percent of the lesions occurred in T₂-weighted hyperintense areas already found in previous examinations. Excluding each patient's first and last scan, 64 newly enhancing lesions were observed. In 50% of the newly enhancing lesions, Gd enhancement was no longer evident on the subsequent scan, suggesting that the duration of enhancement was 4 weeks or less. Seven clinical relapses occurred in six patients, all with concurrent Gd enhancement. Gadolinium-enhancing lesions were noted in 18 MRI examinations . . . [Full Text PDF of this Article]

Author Affiliations
Cleveland, Ohio

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