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Debra A. Katz, MD; Joseph R. Berger, MD
Department of Neurology University of Miami School of Medicine 1501 NW Ninth Ave Miami, FL 33136

Arch Neurol. 1990;47(6):620-621.

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In Reply.

—Although the incidence of neurosyphilis in our series of human immunodeficiency virus-infected patients did not reach statistical significance when compared with the incidence reported by McArthur,¹ there is a marked increase in neurosyphilis in human immunodeficiency virus-infected patients vs non-human immunodeficiency virus-infected patients. During the same time period, 15 cases of neurosyphilis were documented at our hospital in non-human immunodeficiency virus-infected patients with a total of 29 507 non-human immunodeficiency virus-infected patients hospitalized for medical complaints, giving an incidence of 0.05% in non-human immunodeficiency virus-infected patients. The incidence of neurosyphilis in human immunodeficiency virus-infected patients compared with non-human immunodeficiency virus-infected patients is certainly significant (P <.0001), and we conclude that, in our population, neurosyphilis is relatively common in patients with acquired immunodeficiency syndrome.

A recent report by DelRio and colleagues² supports the association between human immunodeficiency virus infection and neurosyphilis. These investigators ascribed an increase . . . [Full Text PDF of this Article]

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