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Fuad Lechin, MD
Apartado 80983 Caracas 1080-A, Venezuela

Arch Neurol. 1990;47(4):382.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

In Reply.

—We agree with Ecker's comments as to standard labeling of trigeminal neuralgia or, what he calls "classic... tic douloureux."¹ Nonetheless, we have treated atypical as well as classic patients (not included in our double-blind study), with results similar to those that appeared in our article, where we only included those patients who had no periods of spontaneous remission; no refractory periods were observed either. Normally, we use doses much lower than required for a double-blind study, thus reducing side effects considerably.

In our opinion, pain location and projections correspond to involvement of distinct central topographical areas of the brain-stem sensory trigeminal nuclear complex² related to the same neurochemical disorders: namely, a deficiency of central serotonergic activity.

Following this trend, we have used different neuropharmacological manipulations, ie, a combination of drugs that interfere with central noradrenergic transmission (75 µg of clonidine plus 5 mg of levopromazine or . . . [Full Text PDF of this Article]

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