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  Vol. 47 No. 4, April 1990 TABLE OF CONTENTS
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Pimozide Therapy for Trigeminal Neuralgia

Arthur Ecker, MD, PhD
603 Crawford Ave Syracuse, NY 13224

Arch Neurol. 1990;47(4):382.

Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To the Editor.

—In their article, Pimozide Therapy for Trigeminal Neuralgia, Lechin et al1 have demonstrated relief of chronic (8 to 17 years) pain in the lower two thirds of the face by the use of pimozide in doses that caused "physical and mental retardation and other symptoms." But was this "trigeminal neuralgia" the classic major paroxysmal pain also known as tic douloureux?

The equal numbers of men and women and also the more frequent involvement of the left side of the face than the right are not characteristic of tic douloureux. Likewise, "periods of constant less intense pain" are not tic douloureux, although they may accompany it. Was the pain strictly unilateral? Had there been periods of spontaneous complete remission? Were there refractory periods?

In my experience of several hundred cases of tic douloureux, effective medication or surgery either prevents the pain or fails to do so2 . . . [Full Text PDF of this Article]



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