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  Vol. 47 No. 3, March 1990 TABLE OF CONTENTS
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Significantly Higher Levels of Soluble Interleukin 2 in Patients With Relapsing-Remitting Multiple Sclerosis Compared With Healthy Subjects

R. Capra; F. Mattioli; N. Marciano'; L. A. Vignolo
Clinica Neurologica

M. Bettinzioli; P. Airo'; R. Cattaneo
Institute of Immunology University of Brescia Piazza Spedali Civili 1 25125 Brescia, Italy

Arch Neurol. 1990;47(3):254.

Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To the Editor.

—Greenberg et al1 recently reported that elevated levels of a soluble form of the interleukin 2 receptor (sIl-2r) released by activated lymphoid cells2 are found in the serum samples of patients affected by chronic progressive multiple sclerosis. An increased expression of membrane-bound interleukin 2 receptor on peripheral blood lymphocytes in patients with a relapsing-remitting form of multiple sclerosis has also been described.3 Therefore, we have measured the levels of sIl-2r in the serum samples obtained from 34 patients with clinically defined4 relapsing-remitting multiple sclerosis using an enzyme-linked immunosorbent assay (Tcell Science, Cambridge, Mass). Nine patients (7 females, 2 males; mean age, 29.2 years) were studied during an acute exacerbation, while 25 patients (17 females, 8 males; mean age, 38.9 years) were studied in a period of clinical remission of at least 6 months' duration. None of the patients had taken steroids during the . . . [Full Text PDF of this Article]



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