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MAJ Andrew C. Peterson, MC, USA
CPT Michael S. Dew, MC, USA
LTC Larry K. Powe, MC, USA
Neurology Service Department of Medicine Letterman Army Medical Center Presidio of San Francisco, CA 94129-6700

Arch Neurol. 1989;46(5):481-482.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To the Editor.

—In a recent article, Glantz et al¹ reported frequent changes in the magnetic resonance imaging (MRI) findings for patients with myotonic dystrophy (MD). These MRI changes were ventriculomegaly and patchy areas of increased T₂ signal in the white matter. These findings were only noted in patients with congenital or adult-onset MD.

We describe a series of five patients from two unrelated families, all with juvenile-onset MD. Although the literature is vague in delineating congenital from juvenile and adult forms of MD, we define juvenile MD as having an onset in the first to second decade, and an absence of hypotonia, significant respiratory distress, facial diplegia with poor suck, or contractures at birth.^2-4 None of these patients show ventriculomegaly, and all have abnormal areas of increased T₂ signal consisting of thin periventricular rimming and multiple focal areas in the white matter deep to the gray-white . . . [Full Text PDF of this Article]

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