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R. D. C. Elwes, MB, MRCP; E. H. Reynolds, MD, FRCP
Department of Neurology Kings College Hospital Denmark Hill London, SE5 9RS, England

Arch Neurol. 1988;45(5):490-491.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To the Editor.

—May we comment on the controversy between Hauser¹ and Hart and Easton² on the subject of seizure recurrence after a first unprovoked seizure and the implications for treatment, as much of the debate centers on our own study?³

In his figure, Hauser¹ compares our³ high (71%) recurrence rate after a single seizure with the moderate (55%) and low (27%) three-year recurrence rates in the studies by himself and his colleagues at Rochester, Minn,⁴ and Minneapolis,⁵ respectively. There are many possible explanations for the variation in these three (and other²) studies, but two factors appear most important to us. First, in both the Rochester and Minneapolis studies, approximately two thirds of the patients were actually treated with anticonvulsants, whereas none of our patients were so treated. This is very likely to have reduced the overall recurrence rate in the American studies. It . . . [Full Text PDF of this Article]

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