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An Indication for Therapeutic Embolization?

Allan J. Fox, MD; Fernando Viñuela, MD

Arch Neurol. 1986;43(5):510-511.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The phenomenon of hemodynamic "steal" has been used to explain progressive neurological deficits in patients with large cerebral arteriovenous malformations (AVMs).^1-7 According to this theory, the sump effect of an AVM competes with the surrounding brain for blood flow, causing relative ischemia that can slowly increase over time. Progressive neurological deficit associated with inoperable AVMs has been considered to be an indication for flow-directed sphere embolization.^3,8,9

The development of techniques for safe, direct, superselective catheterization, both by femoral placement of calibrated-leak balloon catheters^10-13 and by direct surgical catheterization at craniotomy,^10,13-15 has allowed for the embolic injection of isobutyl-2-cyanoacrylate (IBC), a fast-polymerizing tissue adhesive, into AVMs. The embolization techniques using this approach have evolved to include therapy of large, strategically placed AVMs with multiple feeders.¹⁵ Our series of patients treated with IBC includes three who showed remarkable functional recovery of paralyzed limbs during or following IBC . . . [Full Text PDF of this Article]

Author Affiliations
From the Departments of Diagnostic Radiology and Clinical Neurological Sciences, University of Western Ontario, London.

Footnotes
Accepted for publication May 28, 1985.

Reprint requests to Neuroradiology Section, Department of Diagnostic Radiology, University Hospital, Box 5339, Postal Station A, London, Ontario, Canada N6A5A5 (Dr Fox).

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