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S. S. Pollock, MD, MRCP; T. M. Pollock, FFCM, FRCP; M. J. G. Harrison, DM, FRCP
Manchester Royal Infirmary Oxford Road Manchester M13 9WL, England

Arch Neurol. 1986;43(2):106.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To the Editor.

—We read with interest the report by Rapp et al¹ of the occurrence of ampicillin-resistant Listeria monocytogenes meningitis in a previously healthy 14-year-old athlete. We have recently reviewed 54 cases of proven juvenile and adult listerial infection of the central nervous system (CNS) reported to the Public Health Laboratory Service in England and Wales between 1975 and 1980.² Of the ten patients who received ampicillin as the initial sole antibiotic, resistance to the drug was noted in two instances, but recovery followed a change to chloramphenicol. However, the latter drug, which was used as the initial therapy in five cases, also had to be changed in two instances because of resistance. Moreover, one patient, a woman aged 63 years with diabetes and pemphigus for which she was receiving gold sodium thiomalate, cosyntropin, and azathioprine, developed a fatal agranulocytosis. It has been reported³ that the . . . [Full Text PDF of this Article]

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