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F. Frank LeFever, PhD
Neuropsychology Laboratory Helen Hayes Hospital Route 9W West Haverstraw, NY 10993

Arch Neurol. 1986;43(1):9.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To the Editor.

—A recent letter¹ reports treatment of ataxia with propranolol hydrochloride, seeks other reports of trials with ataxia, and asks if there is evidence for a central or cerebellar effect of the drug. Its use with familial, senile, and essential tremor² and subsequent extension to action tremor following head injury³ has been followed by one other report of use with ataxia.⁴ Let us hope that citing these two reports together will encourage further study.

We have used propranolol to reduce disinhibited aggression after head injury, and this use has been extensively studied elsewhere.^5-8 These positive findings suggest, without proving, central action. Also suggestive are reports of use against florid psychoses,⁹ some types of panic,¹⁰ and narcolepsy.¹¹ One should also consider the evidence that reduction of heightened urinary adrenaline with propranolol in alcohol withdrawal¹² is mediated by action on brain . . . [Full Text PDF of this Article]

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