This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Antonio Vela-Bueno, MD
Sleep Laboratory Department of Clinical Neurophysiology Hospital Clinico de San Carlos Madrid, Spain, and Sleep Research and Treatment Center Pennsylvania State University College of Medicine Milton S. Hershey Medical Center Hershey, PA 17033

Anthony Kales, MD; Constantin R. Soldatos, MD
Sleep Research and Treatment Center Pennsylvania State University College of Medicine Milton S. Hershey Medical Center Hershey, PA 17033

Arch Neurol. 1985;42(2):110.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

In Reply.

—The patient described by Thorpy et al¹ is clearly different from any of the patients with Prader-Willi syndrome in our study. Their patient with adult-onset muscular atrophy was unable to sustain the supine position "for more than a few minutes because of dyspnea." For this patient "the maximum duration of sleep without an arousal was two minutes," resulting in a sleep efficiency of only 44%. In contrast, we did not observe any relationship between any type of breathing difficulty and arousal.² In fact, in the one patient whose oxygen saturation was monitored, the desaturation observed continued during REM sleep for ten to 15 minutes without an arousal. During this time the oxygen saturation levels were maintained below 50%.

Also, there was no evidence that a SOREMP, which was present in five of our patients, resulted from chronic REM sleep deprivation due to REMrelated hypoventilation. The overall disturbance of . . . [Full Text PDF of this Article]

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?