This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Louise Charest, MD; Pierre Duquette, MD
Multiple Sclerosis Clinic Hôpital Notre-Dame Montreal, Quebec Canada H2L 4K8

Arch Neurol. 1984;41(7):703-704.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To the Editor.

—In his recent article, Weitkamp¹ suggests an interaction between sex genes and autosomal genes in determining susceptibility to multiple sclerosis (MS) in some but not all persons. His calculations were based on families with more than one person afflicted with MS. We would like to contribute further to this aspect.

Subjects and Methods.

—We have studied the distribution of HLA according to sex in nonfamilial cases of MS. This was done in two groups of patients, one from the MS clinic in London, Ontario (data supplied by G. C. Ebers, MD, written communication, July 1982), one from the two MS clinics in Montreal (HLA typing performed and supplied by G. Lamoureux, MD, written communication, July 1981). Controls were chosen from among normal persons from the same area. A total of 328 patients with MS (nonrelated), 208 women and 120 men, and 467 controls, 230 women and . . . [Full Text PDF of this Article]

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?