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Miles E. Drake, Jr, MD

Arch Neurol. 1983;40(7):453-454.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Amyotrophic lateral sclerosis (ALS) is classically a disease of motor neurons and has clinical manifestations involving the motor system, although cramps may occur.¹ Paresthesias are frequently described, particularly at the onset of weakness and muscular atrophy.² Chronic pain has not been reported in this disorder, to my knowledge. Motor neuron disease may be associated with dementia, parkinsonism, or other neurologic disorders,³ and pathologic involvement extending beyond the motor system has been reported, particularly in the posterior column pathways.⁴ This report concerns a patient with clinically and electromyographically typical ALS in whom a concomitant chronic central pain syndrome developed, for which no additional cause could be found.

REPORT OF A CASE

Weakness, atrophy, and fasciculations of the left lower extremity developed in a 54-year-old woman in 1979. In 1980 she underwent lumbar laminectomy without relief of symptoms. Weakness, wasting, and fasciculations subsequently progressed in the left . . . [Full Text PDF of this Article]

Author Affiliations
From the Division of Neurology, Department of Medicine, Duke University Medical Center, Durham, NC. Dr Drake is now with the Department of Neurology, Ohio State University, Columbus.

Footnotes
Accepted for publication Dec 16, 1982.

Reprint requests to Department of Neurology, Ohio State University Hospitals, 463 Means Hall, 1655 Upham Dr, Columbus, OH 43210.

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