This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (51)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

ANDREW G. ENGEL, M.D.

Arch Neurol. 1961;4(6):663-674.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Introduction

Hyperthyroidism in combination with myasthenia gravis, thyrotoxic myopathy, periodic paralysis, exophthalmic ophthalmoplegia, and acute thyrotoxic encephalomyopathy have been recognized as separate clinical entities.^1,2 Thyrotoxic myopathy and periodic paralysis remit upon treatment of the hyperthyroidism. Exophthalmic ophthalmoplegias may pursue a course independent of thyroid secreting activity. Acute thyrotoxic encephalomyopathy may be but a form of fulminating myasthenia gravis appearing in a thyroid crisis.^3,4 The relationship between hyperthyroidism and myasthenia gravis remains undefined.

Estimates of the frequency of the occurrence of hyperthyroidism in patients with myasthenia gravis vary from 3% to 8.8%.^2,5-7 The higher percentage in the more recent series of Silver and Osserman⁷ is perhaps the more accurate one. An inverse relationship between levels of thyroid activity and the severity of the myasthenia gravis has been endorsed by Thorner, McEachern, and Parnell, and Maclean and Wilson: either therapeutic or spontaneous abatement of the hyperthyroid state . . . [Full Text PDF of this Article]

Author Affiliations
ROCHESTER, MINN.

National Institute of Neurological Diseases and Blindness, National Institutes of Health, U.S. Public Health Service, U.S. Department of Health, Education, and Welfare, Bethesda, Md.

Footnotes
Received for publication Dec. 12, 1960.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?