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Experimental Concussion AccelerationPathology and Mechanics
REINHARD L. FRIEDE, M.D.
Arch Neurol. 1961;4(4):449-462.
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Introduction
Concussion is a transient reversible alteration of the central nervous system of immediate onset resulting from an impact to the head. It is defined physiologically by a temporary abrogation of certain reflex functions, and pathologically by the absence of gross destruction of brain substance, but presence of finer cellular changes; both psysiological and pathological evidences indicate a particular affection of the brain stem.
Denny-Brown and Russell5 distinguished an acceleration concussion of the freely movable head from a compression concussion of the rigidly fixed head. The present investigation is limited to the neuropathology and mechanics of experimental acceleration concussion in cats; the relationship of acceleration concussion to compression concussion will be discussed on the basis of these findings.
Two experimental series are reported in this article: the first part describes the histopathology of cats with concussions compared to the symptoms and the mechanical forces involved. The second part describes
. . . [Full Text PDF of this Article]
Author Affiliations
ANN ARBOR, MICH.
Footnotes
Received for publication Nov. 30, 1960.
With the technical assistance of Bob Horne.
Laboratory of Neuropathology, Medical Center, University of Michigan, and Wright Air Development Division, Aero-Space Medical Laboratories, Dayton, Ohio.
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