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Preliminary Experimental and Clinical Observation

BYRON M. BLOOR, M.D.; JOHN FRICKER, A.B.; FRANK HELLINGER, M.D.; HIRO NISHIOKA, M.D.; JOHN McCUTCHEN

Arch Neurol. 1961;4(1):37-46.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The circulation of the brain has been the object of more speculation and study than any other part of the body. All present methods of estimating cerebral blood flow, however, leave much to be desired. Since, for many practical purposes we are not interested in the blood flow per se but in whether or not the oxygenation of the brain is adequate, we have attempted to approach the problem of quantitative brain oxygen tension directly.

The prime consideration was "what" to measure that might justifiably be called "mean tissue oxygen tension." As pointed out by Bronk et al.¹ and Bloor et al.² the spatial resolution of the oxygen electrode is such that the absolute value obtained from the cortex varies greatly with its position relative to blood vessels. Other obvious problems arise in using the exposed cortex, such as pulsation, movement, variations in electrode pressure, etc. However, . . . [Full Text PDF of this Article]

Author Affiliations
CLEVELAND

From the Department of Surgery (Division of Neurosurgery), Western Reserve University School of Medicine at Cleveland Metropolitan General Hospital and University Hospitals, Cleveland.

Footnotes
Accepted for publication Oct. 1, 1960.

Presented, in part, at the meeting of the American Academy of Neurological Surgery, Pebble Beach, Calif., October, 1959.

This investigation was supported by research grant B-1535 and B-1535C1 from the National Institute of Neurologic Disease and Blindness, National Institutes of Health, U.S. Public Health Service.

We are deeply indebted to Max D. Liston and his colleagues of Beckman Instruments, Inc., for their major effort in the development of this electrode.

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