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HENN KUTT, M.D.; LEWIS J. HURWITZ, M.D.; SELIG M. GINSBURG, M.D.; FLETCHER McDOWELL, M.D.

Arch Neurol. 1961;4(1):31-36.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Elevations of the cerebrospinal fluid total protein have been reported in patients with diabetes mellitus.^1-7 Some authors believe that the spinal fluid protein increase is found only in the presence of clinical evidence of diabetic neuropathy or in diabetic patients with a history of a recent cerebrovascular accident.⁶ However, other factors such as generalized vascular disease may also contribute to the abnormalities of spinal fluid proteins.

This paper is concerned with the study of total protein and its fractions demonstrated by starch gel electrophoresis in the cerebrospinal fluid of diabetic patients. Gel electrophoresis⁸ was used because of its exceptional resolving power. These findings were correlated with the presence or absence of vascular and/or neurological complications.

Materials and Methods

Eighty-four patients with diabetes mellitus from the Second (Cornell) Medical and Neurological Services of Bellevue Hospital were investigated in this study. There were 43 male and 41 female patients . . . [Full Text PDF of this Article]

Author Affiliations
NEW YORK

From the Neurological Service of the Cornell Medical Division of Bellevue Hospital, and the Department of Medicine, Cornell University Medical College.

Footnotes
Accepted for publication Oct. 6, 1960.

Present address of Dr. L. J. Hurwitz: The National Hospital, Queen Square, London, England.

This work was supported in part by research grant No. 215 from the National Multiple Sclerosis Society and in part by special clinical traineeship No. 267 (CI), from the Institute of Neurological Diseases and Blindness, U.S. Public Health Service.

Starch hydrolyzed for gel electrophoresis manufactured by Connaught Medical Research Laboratories, Toronto, Canada.

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