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William J. Weiner, MD; Paul A. Nausieda, MD

Arch Neurol. 1982;39(7):451-452.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The blepharospasm-oromandibular dystonia syndrome was first described by Meige in 1910.¹ He described patients afflicted with preponderantly symmetric dystonic spasms of the facial muscles who also might have dystonic movements involving other midline muscle groups. After the original description of this bizarre and oftentimes disabling movement disorder, little was mentioned in the medical literature until 1972, when reports of isolated oromandibular dystonia² and oromandibular dystonia with blepharospasm appeared.³

Since that time there has been increasing attention paid to this syndrome, including a suggestion that it be termed Brueghel's syndrome, after the Dutch painter who created portraits that captured the distinctive dystonic facial postures seen in this syndrome.⁴ Marsden has described the largest series of these patients and has noted that the syndrome is adult onset (usually in the sixth decade), with the initial symptom being either blepharospasm or oromandibular dystonia alone or, most frequently, a combination . . . [Full Text PDF of this Article]

Author Affiliations
From the Department of Neurological Sciences, Rush-Presbyterian-St Lukes Medical Center, Chicago.

Footnotes
Accepted for publication Nov 1, 1981.

Reprint requests to Department of Neurological Sciences, Rush-Presbyterian-St Lukes Medical Center, 1725 W Harrison St, Chicago, IL 60612 (Dr Weiner).

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