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Lymphomatoid Granulomatosis Manifested as a Mass in the Cerebellopontine Angle
Jonathan Hood;
Edward R. Wilson, Jr, MD, PhD;
C. Bruce Alexander, MD;
Andrew Flint, MD;
Kang-Jey Ho, MD, PhD
Arch Neurol. 1982;39(5):319-320.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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Lymphomatoid granulomatosis, first described by Liebow et al1 in 1972, is a rare clinical entity characterized by angiocentric, angiodestructive lymphoreticular proliferation and granulomatous reaction. It initially involves primarily the lung, and in a subsequent sarcomatous stage extrapulmonary tissues are involved. We have recently encountered a case of lymphomatoid granulomatosis with nodular pulmonary infiltrates and symptoms of a rapidly growing mass in the cerebellopontine angle. Central nervous system involvement is by no means uncommon, as it occurs in at least 20% of all patients with lymphomatoid granulomatosis.1-3 In patients with rapidly developing CNS symptoms associated with nodular lung lesions, lymphomatoid granulomatosis should be considered a strong candidate in the differential diagnosis.
REPORT OF A CASE
In a 54-year-old man, malaise, restlessness, intermittent fever, and a 15-kg weight loss occurred during the year before admission. Initially, he was treated for a bacterial pneumonia because of bilateral nodular infiltrates shown on
. . . [Full Text PDF of this Article]
Author Affiliations
From the Department of Pathology, University of Alabama in Birmingham Medical Center, and Veterans Administration Hospital, Birmingham.
Footnotes
Accepted for publication Sept 5, 1981.
Reprint requests to Department of Pathology, University of Alabama in Birmingham Medical Center, 1919 Seventh Ave S, Birmingham, AL 35233 (Dr Ho).
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