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Primary Malignant Melanomatosis of the MeningesClinical Course and Computed Tomographic Findings in a Young Child
Darrell E. Crisp, MD;
Joel A. Thompson, MD
Arch Neurol. 1981;38(8):528-529.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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Neurocutaneous melanosis is an uncommon disorder that is classified among the phakomatoses. Fully expressed, it consists of multiple cutaneous nevi and a proliferation of melanocytes in the leptomeninges.1 A forme fruste is isolated benign melanosis of the meninges, which may undergo malignant transformation, most often during adult life.2 We report the unusual clinical course and computed tomographic (CT) findings in a case of presumed primary malignant melanomatosis of the meninges without skin nevi in a child.
REPORT OF A CASE
A 41/2-year-old girl had recurrent headaches in July 1979, and a tentative diagnosis of migraine was made. Recurrence of symptoms in September led to complete examination that included a CT scan, which was normal. Soon afterward, she was admitted to a hospital following a seizure. Lumbar puncture (LP) revealed a pressure of 300 mm H2O, 30 WBCs, 20 RBCs, a glucose level of 30 mg/dL
. . . [Full Text PDF of this Article]
Author Affiliations
From the Division of Pediatric Neurology, Department of Pediatrics, University of Utah College of Medicine and Primary Children's Medical Center, Salt Lake City.
Footnotes
Accepted for publication Jan 15, 1981.
Reprint requests to Department of Pediatrics, University of Utah College of Medicine, 50 N Medical Dr, Salt Lake City, UT 84132 (Dr Thompson).
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