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Lawrence R. Jenkyn, MD; David W. Roberts, MD; Nancy J. Reed, MD; Richard E. Nordgren, MD; Richard L. Saunders, MD; George Margolis, MD
Dartmouth Medical School Hanover, NH 03755

Arch Neurol. 1980;37(6):397-398.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To the Editor.—

The use of Collins' Law¹ instead of five-year survival rates in the assessment of the risk of recurrence of ependymoma has been advocated.² The law states that a tumor grows in a patient at a certain rate unique to that patient; thus, after ablation, the tumor will become symptomatic a second time when it reaches a size comparable with that at the time of initial diagnosis. The longest time over which this amount of regrowth can occur is equivalent to the time that would have been available for the first growth of the tumor had it begun at conception (the age of the patient at the time of first diagnosis plus nine months). A symptom-free ratio may also be defined (independent of age) as the ratio of the symptom-free interval to the interval from

Left, Ependymoma of patient at age 10 years (hematoxylin-eosin [H-E], x . . . [Full Text PDF of this Article]

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