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Juan Narbona, MD
Child Neurology Unit

Carlos D. Crisci, MD
Department of Allergology Section of Immunology

Ignacio Villa, MD
Department of Pediatrics University of Navarra Pamplona, Spain

Arch Neurol. 1980;37(5):325.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To the Editor.—

In the interesting article by Orrison and Robertson (ARCHIVES 36:29-31, 1979) concerning the pathogenesis of congenital ocular motor apraxia (COA), two familial cases are reported and the role that genetic factors may play in the development of this syndrome are discussed. To our knowledge, neither in these two cases nor in the others at present reported^1-5 have the patients' immune status been discussed. Recently, we have observed two children, a brother and sister, with COA and selective IgA deficiency, which made us wonder whether there might exist a relationship between "familial COA" and ataxia-telangiectasia.

Report of Cases.—

A 4-year-old girl and her brother (aged 21/2 years) were first seen in December 1978, with typical COA, ataxia in gait since they first began walking, and clumsiness in fine movements of the upper limbs. The girl's abnormalities of eye movement have improved during the last year. Growth and development . . . [Full Text PDF of this Article]

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