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Guillain-Barrélike Polyneuropathy After Renal TransplantPossible Association With Cytomegalovirus Infection
James F. Bale, Jr, MD;
Neal S. Rote, PhD;
Linda C. Bloomer, PhD;
Patrick F. Bray, MD
Arch Neurol. 1980;37(12):784.
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Guillain-Barré-like polyneuropathy developed in a 40-year-old man three months after a successful kidney transplant. Serologic evidence from blood and CSF suggests that this patient's illness was related to a recent infection with cytomegalovirus.
REPORT OF A CASE
This 40-year-old man had been healthy until 1977, when polydipsia and hematuria developed. Examination at another hospital showed impaired renal function, and in October 1977 an open renal biopsy disclosed changes consistent with rapidly progressive glomerulonephritis. Prednisone was prescribed.
On initial admission to the University of Utah Medical Center, Salt Lake City, in November 1978, he appeared chronically ill and had a blood pressure (BP) of 172/110 mm Hg. The results of his neurologic examination were normal. Laboratory studies disclosed deterioration in renal function, with a serum creatine concentration of 15.4 mg/dL and BUN concentration of 125 mg/dL. An arteriovenous shunt was placed and hemodialysis was initiated.
In July 1979 the patient
. . . [Full Text PDF of this Article]
Author Affiliations
From the Division of Pediatric Neurology, Departments of Pediatrics and Neurology (Drs Bale, Bloomer, and Bray), and Obstetrics and Gynecology (Dr Rote), Univeristy of Utah College of Medicine, Salt Lake City.
Footnotes
Accepted for publication April 23, 1980.
Reprints not available.
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