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Phillip M. Green, MD
Marshfield Clinic 1000 N Oak Ave Marshfield, WI 54449

Arch Neurol. 1980;37(10):676.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To the Editor.—

Drs Mitsuyama and Takamiya in their presentation of a case of presenile dementia with motor neuron disease (ARCHIVES 36:592-593, 1979) suggested that a new entity previously unclassified has been identified. I believe this reclassification of a well-described form of Creutzfeldt-Jakob disease, is premature. Kirschbaum,¹ in an extensive monograph, reviewed 150 cases of Creutzfeldt-Jakob disease. Using this classification, 30 of the patients were identified as having varieties of motor neuron impairment. The courses of these patients were much longer than those of classic Creutzfeldt-Jakob disease and ranged from nine to 132 months, with the mode being 17 months. This is fully in keeping with the patient described, whose course was 18 months. These patients frequently do not have the myoclonus or characteristic EEG findings of the more rapid presentation of Creutzfeldt-Jakob disease. I urge the authors to reexamine their patient and the previous patients described in their . . . [Full Text PDF of this Article]

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