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  Vol. 33 No. 11, November 1976 TABLE OF CONTENTS
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Diphasic Response to Corticosteroids in Idiopathic Relapsing Polyneuropathy

R. C. Griggs, MD
Depts of Neurology, Medicine, and Pediatrics Univ of Rochester School of Medicine and Dentistry Rochester, NY 14642

R. Nash, MD
Dept of Neurology State Univ of New York Upstate Med Center Syracuse, NY 13210

Arch Neurol. 1976;33(11):794-795.

Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The editor will be pleased to receive correspondence of 250 words or less that pertains to material published in the Archivesor to other matters of interest to its readers. Letters should be type-written double-spaced and should be clearly marked "For Publication." No more than 5 references are permitted and illustrations and tables are acceptable only when essential to the message.

Corticosteroid treatment has been associated with prolonged remissions in chronic idiopathic relapsing polyneuritis (IRP).1-4 Recently, it has been noted that this response may require prolonged therapy,2 but can be maintained with alternate-day corticosteroid administration.3 Some authors have not noted a beneficial effect5 or have noted a worsening with corticosteroid therapy.4.6 The possibility that an initial worsening might precede improvement has not been considered.

We have treated a man with IRP whose initial response to corticosteroids was a dramatic worsening on each of four occasions. Although this . . . [Full Text PDF of this Article]



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