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Koch's Postulates and Slow Infections of the Nervous System
Richard T. Johnson, MD;
Clarence J. Gibbs, Jr., PhD
Arch Neurol. 1974;30(1):36-38.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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Haven't you guys ever heard of Koch's postulates?
Anonymous Voice From AN Audience, 1973
The medical literature of the past ten years has presented a bewildering array of data linking viral infections to chronic human neurological disease. There have been reports of the recovery of a variety of viruses from the brains of patients, the transmission of some diseases to primates, the demonstration of globulin or viral antigens in neural and nonneural tissues, electron microscopic observation of virus-like particles in brain, and epidemiologic data suggesting probable viral causes for diseases. Certainly, these reports raise the question of what criteria exist for establishing a virus as the cause of a disease. In response to this question, Koch's postulates need review both within the context of his times and within the limitations of contemporary virology; possibly then some acceptable criteria tentatively can be proposed for relating viruses to chronic disease.
. . . [Full Text PDF of this Article]
Author Affiliations
Baltimore, Md; Bethesda, Md
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