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HERBERT LOURIE, M.D.; THOMAS G. HOLMES, M.D.; WILLY WEINSTEIN, M.D.; HENRY G. SCHWARTZ, M.D.; JAMES L. O'LEARY, M.D.

Arch Neurol. 1960;3(2):163-176.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Hypothermia has proved to be a doubleedge sword, for while protecting the brain against anoxia it threatens the heart with arrhythmia. This undesirable effect has led to attempts to cool the brain profoundly, while lowering the heart temperature only moderately. Several groups^1,12,14,17 have accomplished this by shunting carotid blood through a heat exchanger. Woodhall and collaborators²⁷ used a circuit whereby jugular blood is oxygenated and cooled and then recirculated through the brain. We were encouraged by the report of Kimoto et al.,¹² who cited successful use of an extracorporeal carotid cooling system as an adjunct to open heart surgery in 9 of 11 human cases.

The present study was undertaken to gain experience with the new technique of blood-stream cooling, and to enlarge on observations reported by others. We sought specifically to compare surface cerebral temperatures with those in the depths of the cerebrum and cerebellum, and . . . [Full Text PDF of this Article]

Author Affiliations
St. Louis

From the Divisions of Neurosurgery and Neurology and the Beaumont-May Institute of Neurology, Washington University School of Medicine.

Footnotes
Accepted for publication Jan. 28, 1960.

Aided by a grant from the Allen P. and Josephine B. Green Foundation.

Now at State University of New York College of Medicine, Syracuse Upstate Medical Center (Dr. Lourie). U.S. Public Health Service graduate research fellow, Institute of Neurological Diseases and Blindness, National Institutes of Health (Dr. Weinstein).

Tele-thermometer Model 41 TD, Yellow Springs Instrument Co., Yellow Springs, Ohio.

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