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Two Classes of Dysergic Brain Abnormality and Their Conditions of Occurrence
Ronald E. Myers, MD, PhD
Arch Neurol. 1973;29(6):394-399.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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Quite different patterns of brain abnormality result from impaired tissue energy availabilities of different severities. Unfortunately, no nomenclature exists which adequately differentiates between these disparate energy deficiency states. Thus, it is proposed to designate any state of abnormal tissue energy availability as a dysergic state, basing the term on the Greek prefix dys-, signifying a disorder or malady of, and the Greek word ergon, meaning to work. Hypoergia and anergia may designate states of impaired and absent tissue energy availability, respectively.
Still further attention to definition of terms is demanded since several other specific pathophysiologic states which define specific patterns of brain abnormality remain frequently misused. Though the distinction between anoxia and hypoxia is a very old one, a frequent confusion of these terms still remains. Let it therefore be reemphasized that anoxia implies a total lack of oxygen availability to the tissues, while hypoxia implies only its reduced presence
. . . [Full Text PDF of this Article]
Author Affiliations
Bethesda, Md
From the Laboratory of Perinatal Physiology, National Institute of Neurological Diseases and Stroke, National Institutes of Health, Bethesda, Md.
Footnotes
Read before the symposium held at New York Hospital—Cornell Medical Center: The Threshold and Mechanisms of Anoxic-Ischemic Brain Injury, New York, June 10,1973.
Reprint requests to Laboratory of Perinatal Physiology, National Institute of Neurological Diseases and Stroke, National Institutes of Health, Bethesda, Md 20014 (Dr. Myers).
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