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  Vol. 29 No. 6, December 1973 TABLE OF CONTENTS
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  PAPERS READ BEFORE THE SYMPOSIUM HELD AT NEW YORK HOSPITAL-CORNELL MEDICAL CENTER: THE THRESHOLD AND MECHANISMS OF ANOXIC-ISCHEMIC BRAIN INJURY, NEW YORK, JUNE 10, 1973
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"Ischemic Neuronal Disease" of Spielmeyer

A Reevaluation

Jan Cammermeyer, MD

Arch Neurol. 1973;29(6):391-393.

Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The fundamental studies of Spielmeyer1 led to the identification of various types of neuronal changes and the subsequent stand-ardization and development of neuropathologic research. From the vast material examined, Spielmeyer and his colleagues formulated a concept of a vascular origin for many of the cerebral lesions and, over the years, only slight modifications to the original concept have been advanced. I shall here merely mention that while most investigators have agreed that the "ischemic neuronal disease" of Spielmeyer represents an irreversible pathologic process, Camerer2 pointed out the similarity of such changes to a postmortem autolytic process, and Lindenberg3 advocated the combination of an intravital and a postmortem cell reaction.

In systematic studies of human neuropathologic material from a general hospital, lesions attributable to circulatory disturbances are commonly found. Further analysis of such material will often indicate that the cerebral blood flow has been impaired . . . [Full Text PDF of this Article]


Author Affiliations

Bethesda, Md

From the Laboratory of Neuropathology and Neuroanatomical Sciences, National Institute of Neurological Diseases and Stroke, National Institutes of Health, Public Health Service, US Department of Health, Education, and Welfare, Bethesda, Md.


Footnotes

Read before the symposium held at New York Hospital—Cornell Medical Center: The Threshold and Mechanisms of Anoxic-Ischemic Brain Injury, New York, June 10,1973.

Reprint requests to National Institutes of Health, Bldg 9, Room 1E124, Bethesda, Md 20014 (Dr. Cammermeyer).



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