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Autonomic Deficits in Parkinson's Syndrome
Otto Appenzeller, MD, PhD;
Jerry E. Goss, MD
Arch Neurol. 1971;24(1):50-57.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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THE occurrence of autonomic dysfunction in Parkinson's syndrome is widely quoted, but most studies are restricted to clinical impressions. The abnormalities attributed to autonomic disturbances in this disease include sialorrhea, seborrhea, excessive sweating, constipation, sphincter disturbances, dysphagia, postural hypotension, blue mottled skin, and other vasomotor abnormalities, heat intolerance and impotence, to name a few. With the introduction of levodopa for the treatment of Parkinson's syndrome, large numbers of patients have come forth, eager to allow evaluation of their clinical state before, and at intervals after, the start of levodopa therapy. We have tested some autonomic function before and during treatment in 25 patients suffering from Parkinson's syndrome and record the findings in this report.
Patients and Methods
Patients were tested before the start of levodopa therapy and after maximum neurological improvement had been achieved. Fifteen patients were receiving no medication at the time of the baseline tests, all drugs
. . . [Full Text PDF of this Article]
Author Affiliations
Albuquerque, NM
From the departments of neurology (Dr. Appenzeller) and medicine (Drs. Appenzeller and Goss), University of New Mexico School of Medicine, Albuquerque, NM.
Footnotes
Accepted for publication Sept 8, 1970.
Reprint requests to Department of Neurology, University of New Mexico School of Medicine, Albuquerque, NM 87106 (Dr. Appenzeller).
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