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William H. Oldendorf, MD; Warden B. Sisson, MD; Youichi Iisaka, MD

Arch Neurol. 1970;23(1):74-79.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

EARLY in the course of sodium pertechnetate Tc 99m (TcO₄-) human brain scanning there was noted an occasional appearance of regional uptake in the midhemisphere.¹ Witcofski et al² identified this uptake to be in choroid plexus and subsequently demonstrated in vivo the ability of rabbit choroid plexus to concentrate TcO₄from blood.³ The suppression of this uptake by the perchlorate ion (ClO₄-) was also demonstrated.

Employing a ventriculocisternal perfusion (VCP), the in vivo studies presented here demonstrate the remarkable ability of the rabbit choroid plexus to concentrate TcO₄- present in the ventricular fluid. To determine the relative affinity of choroid plexus for TcO₄- and the iodide ion (I-), carrierfree sodium iodide I 131 was included in the perfusion fluid. The rates of removal of these ions from the ventricular fluid were measured, and the choroid plexus and brain tissue concentrations . . . [Full Text PDF of this Article]

Author Affiliations
Los Angeles

From the Research and Medical Services, Wadsworth Hospital, Veterans Administration Center (Drs. Oldendorf and Sisson), and Division of Neurology, Department of Medicine, UCLA School of Medicine (Drs. Oldendorf and Iisaka), Los Angeles.

Footnotes
Submitted for publication Jan 5, 1970; accepted Feb 12.

Reprint requests to Wadsworth Veterans Administration Hospital, Wilshire and Sawtelle Boulevards, Los Angeles 90073 (Dr. Oldendorf).

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