 |
|
Centronuclear Myopathy With Type I Fiber Atrophy and "Myotubes"
Jaap Bethlem, MD;
George K. van Wijngaarden, MD;
Mark Mumenthaler, MD;
A. E. F. Hugo Meijer, PhD
Arch Neurol. 1970;23(1):70-73.
|
|
| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
|
|
|
RECENTLY patients have been described with muscle fibers that resembled the myotubes seen in early fetal life.1-11 In some of these cases, there were many fibers of small diameter, predominantly or exclusively of type I.5,6,9,11
In this paper, a patient is found to have a neuromuscular disease that differs histopathologically from cases described hitherto.
Report of a Case
The patient was a 38-year-old woman. Motor development appeared normal until age 5 years. From that time, there was a slowly progressing paresis of the legs. During pregnancies at age 25 and 27, the weakness increased. There was no diplopia or weakness of the arms. In the family, no other siblings were known to be suffering from a neuromuscular disease. Examination revealed a well-developed woman of average intelligence. There was no ptosis and no weakness of the facial, extraocular, and neck muscles. The strength of the deltoid and biceps
. . . [Full Text PDF of this Article]
Author Affiliations
Amsterdam
From the Neurological Clinic of the University of Amsterdam (Drs. Bethlem and van Wijngaarden), the Neurological Clinic of the University of Bern (Dr. Mumenthaler), and the Laboratory of Pathological Anatomy (Dr. Meijer), University of Amsterdam.
Footnotes
Submitted for publication Jan 23, 1970; accepted March 10.
Reprint requests to Neurological Clinic, Wilhelmina Gasthuis, 1 ste Helmersstraat 104, Amsterdam (Dr. Bethlem).
 CiteULike  Connotea  Del.icio.us  Digg  Reddit  Technorati  Twitter
What's this?
|
