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Incidence in Young Women Receiving Oral Contraceptives

LTC Darrell S. Buchanan, MC; MAJ John H. Brazinsky, MC

Arch Neurol. 1970;22(5):440-444.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

THE USE of oral contraceptive agents has been proposed to predispose to a variety of neurological problems including vascular headaches,^1-5 convulsive seizures, benign intracranial hypertension,⁵ optic neuritis,⁵ and cerebral vascular accidents.^1-9 Arterial thromboses reportedly have been the cause of most of the cerebrovascular accidents. This report concerns two young women who developed dural sinus and cortical venous thromboses while they were taking oral contraceptive agents.

Report of Cases

CASE 1.—An obese, 35-year-old, white woman, gravida 5, para 5, had a past history of eclampsia with her second pregnancy and hypertension with each subsequent pregnancy. Her mother was hypertensive, and her father reportedly died of a cerebral vascular accident at age 38. The patient had gained 4.5 kg (10 lb) during the two months before admission. She had taken norethynodrel and mestranol intermittently for the past two years and was in the last half of a . . . [Full Text PDF of this Article]

Author Affiliations
USA, USA, San Francisco

From the Neurology Service (LTC Buchanan) and Pathology Service (MAJ Brazinsky), Letterman General Hospital, San Francisco.

Footnotes
Submitted for publication Nov 5, 1969; accepted Nov 29.

Read in part before the Symposium on Neurologic Complications of Drug Therapy at the 117th annual convention of the American Medical Association, San Francisco, June 20, 1968.

Reprint requests to PO Box 406, Letterman General Hospital, San Francisco 94129 (LTC Buchanan).

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