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A Case With EEG Evidence of Periodic Brain Dysfunction

Leonard N. Green, MD; Roger Q. Cracco, MD

Arch Neurol. 1970;22(2):166-175.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

THE Kleine-Levin syndrome, first described by Kleine¹ in 1925 and Levin² in 1929, is composed of recurring episodes of sleepiness lasting days, associated with excessive appetite and often with abnormal behavior. It usually affects male adolescents. It is rare; Sours³ did not find one case in reviewing 115 patients with excessive sleepiness who were evaluated at the Columbia-Presbyterian Medical Center from 1932 to 1961. Critchley⁴ stated that only 26 acceptable cases had been reported up to 1962, including 11 personal cases. Since then several more cases have been reported.^5-11

The etiology of the Kleine-Levin syndrome is unknown. Laboratory investigations, including electroencephalographic studies have not revealed abnormalities of the cerebral functions examined.^{4,5,7,9,10,12-14} We describe the case of a patient with the Kleine-Levin syndrome who had markedly abnormal electroencephalogram findings only during episodes of hypersomnolence.

Report of a Case

A 19-year-old white male patient was . . . [Full Text PDF of this Article]

Author Affiliations
Phoenixville, Pa

From the Neurology Service, Department of Medicine, Valley Forge General Hospital (US Army), Phoenixville, Pa. Dr. Green is now at Neurology Service, Department of Medicine, Youngstown Hospital, Youngstown, Ohio, and Dr. Cracco is now at Department of Neurology, Jefferson Medical College, Philadelphia.

Footnotes
Submitted for publication July 2, 1969; accepted Sept 3.

Read in part before the Philadelphia Neurological Society, Nov 3, 1967.

Reprint requests to Neurology Service, Youngstown Hospital, Gypsy Lane and Goleta, Youngstown, Ohio 44505 (Dr. Green).

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