This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Martin H. Feldman, MD; Nathan S. Schlezinger, MD

Arch Neurol. 1970;22(1):1-7.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

MANY explanations have been proposed concerning the etiology of benign intracranial hypertension (BIH).^1-109 The syndrome includes headache, papilledema, increased intracranial pressure, and occasional related visual field defects and sixth nerve palsies.^1-10 The patients are alert, and the electroen-cephalogram is usually normal,¹¹ as are the cerebrospinal fluid (CSF) protein level and cell count. Pneumoencephalogram shows a normal or small ventricular system, and no obstruction of extracerebral CSF patterns.^1-7 Brain edema has been noted on biopsy, with swelling of all cellular elements.¹² Papilledema can occasionally be so severe as to constitute a threat to vision.⁷ The majority of patients experience a self-limiting course, with rare recurrence.¹³

Implicated as causative factors have been the following: (1) obstruction or impairment of intracranial venous drainage^7,14-28; (2) endocrine and metabolic dysfunctions,^29-43 including obesity,^30-33 menstrual disorders,^34,35 pregnancy,^36,37 menarche,³⁸ Addison's disease,³⁹ and hypoparathy-roidism^40-42; (3) exogenously administered drugs,^44-62 including adrenal steroids,^44-51 female sex hormones,^52-54 antibiotics,^55-61 and psychotherapeutic drugs⁶²; and . . . [Full Text PDF of this Article]

Author Affiliations
Philadelphia

From the Jefferson Medical College Hospital, Philadelphia. Dr. Feldman is now at the Department of Anatomy, Albert Einstein College of Medicine, Bronx, NY.

Footnotes
Submitted for publication Aug 25, 1969; accepted Sept 12.

Read in part before the Philadelphia Neurological Society, April 8, 1966.

Reprint requests to the Department of Neurology, Jefferson Medical College Hospital, Philadelphia 19107 (Dr. Schlezinger).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?