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Richard M. Gladstone, MD

Arch Neurol. 1969;21(2):184-192.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

HETEROCHROMIA is an alteration in iris color and structure. Although usually benign, it may be the only clue to an underlying disorder. The purpose of this report is to discuss the development and significance of this finding and to emphasize the importance of recording it.

Description

Aristotle described the condition and called it heteroglaucos. The history books also record that the eastern Emperor Anastasios I was called Dicorus because his eyes were of different colors, and Plutarch states that Alexander the Great had heterochromia.¹

Heterochromia may take two forms: a hypopigmentation of the iris of whatever color, with iris hypoplasia; or a hyperpigmentation, with iris hyperplasia. The color change may involve one eye alone or both eyes and may be partial or complete. The uniocular type in which different parts of the same iris are of different colors is called heterochromia iridis, piebald iris, variegated iris, or iris . . . [Full Text PDF of this Article]

Author Affiliations
Toronto

From the Department of Pediatric Medicine (Neurology), The Hospital for Sick Children, Toronto.

Footnotes
Submitted for publication Feb 14, 1969; accepted Feb 17.

Read before the Fourth Canadian Congress of Neurological Sciences, Montreal, June 1969.

Reprint requests to the Department of Neurology, The Hospital for Sick Children, 555 University Ave, Toronto 2.

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