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Development of Cervical Collateral Network in Chronic Occlusion of the Proximal Portion of the Right Subclavian Artery

Wakou Anazawa, MD; Margaret C. Conrad, PhD; Masahiro Kato, MD; Richard Janeway, MD; James F. Toole, MD

Arch Neurol. 1969;21(1):66-72.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

COLLATERAL channels usually develop in patients with extracranial arterial occlusive disorders which help to keep blood flow constant. Although several radiological studies in man have documented collateral channels, few experimental studies have been performed to elucidate changes in arterial collateral patterns and blood flow distribution in cervical arteries in response to occlusion of a vessel in the neck or chest. This report details the results of an analysis of the collateral channels that develop in response to long standing occlusion of the right subclavian artery proximal to the origin of the right vertebral artery.

Methods

Sixteen mongrel dogs were involved in the present study. Five were used for normal control subjects. In 11 dogs, the right subclavian artery was ligated just proximal to the origin of the right vertebral artery. The animals were allowed to live for from six months to four years. During this time, other hemodynamic studies . . . [Full Text PDF of this Article]

Author Affiliations
Winston-Salem, NC

From the departments of neurology (Drs. Anazawa; Kato; Janeway; and Toole) and physiology (Dr. Conrad), Bowman Gray School of Medicine, and the North Carolina Baptist Hospital (Drs. Janeway and Toole), Winston-Salem, NC. Dr. Conrad is an Established Investigator for the American Heart Association. Dr. Janeway is a Markle Scholar in Medical Science.

Footnotes
Submitted for publication Nov 22, 1968; accepted Jan 24, 1969.

Reprint requests to the Department of Neurology, Bowman Gray School of Medicine, Winston-Salem, NC 27103 (Dr. Janeway).

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