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II. Data Acquisition and Analysis

Rex Hill, MS; John Clifton, MSc; Tom Gallager, DSc; E. James Potchen, MD

Arch Neurol. 1969;20(4):384-387.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

THE COMPLEXITY of data retrieval and burdensome calculations have limited the wide-spread application of the multiprobe inert gas method to the clinical assessment of regional cerebral blood flow (rCBF).

Lassen¹ has attempted to overcome this obstacle by observing the analogue readout of the early curve slope as an index of rCBF. Their approach is far simpler than previously described hand or computer calculations.² However, the analogue method is limited by providing only a flow index rather than calculated rCBF in cc/100 gm/min and by its emphasis of fast flow (cortical) components to the exclusion of white matter flow. This simplified (analogue) modification has been most useful in studying regional autoregulation by observing the early slope before and after the induction of systemic hypertension.

In developing a clinical method to obtain rCBF as an adjunct to carotid arteriography, we considered that it might not be desirable to . . . [Full Text PDF of this Article]

Author Affiliations
St. Louis

From the Edward Mallinckrodt Institute of Radiology and the Biomedical Computer Laboratory, Washington University School of Medicine, St. Louis.

Footnotes
Submitted for publication Oct 2, 1968; accepted Nov 25.

Reprint requests to Mallinckrodt Institute of Radiology, 510 S Kingshighway, St. Louis 63110 (Dr. Potchen).

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