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Memory Loss due to Hippocampal LesionsReport of a Case
Russell N. DeJong, MD;
Hideo H. Itabashi, MD;
John R. Olson, MD
Arch Neurol. 1969;20(4):339-348.
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MEMORY has been defined as that property of the nervous system whereby it is effective both in the storage and the retrieval of information.1 Instances of "pure" memory loss without associated impairment of other intellectual functions and not complicated by the presence of other neurologic signs or symptoms or by clouded or altered states of consciousness are rarely encountered in neurologic practice or reported in the neurologic literature. Memory loss is most frequently found in association with widespread disturbance of cerebral function in conditions such as senile brain disease, the presenile and other organic psychoses, toxic and deficiency states, encephalitis, posttraumatic and postanoxic sequelae, and after electroshock therapy and status epilepticus.2 In all of these, however, there are usually other associated neurologic abnormalities as well as disturbances of other intellectual functions and of consciousness. Even in those conditions in which the lesions are somewhat localized (Korsakoff-Wernicke encephalopathy,
. . . [Full Text PDF of this Article]
Author Affiliations
Ann Arbor, Mich
From the departments of neurology (Drs. DeJong and Itabashi) and pathology (Drs. Itabashi and Olson), University of Michigan Medical Center, Ann Arbor, Mich.
Footnotes
Submitted for publication Oct 29, 1968; accepted Nov 9.
Read before the 93rd annual meeting of the American Neurological Association, Washington, DC, June 17, 1968.
Reprint requests to University Hospital, 1405 E Ann St, Ann Arbor, Mich 48104 (Dr. DeJong).
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